Laboratory of Plant Biotechnologies

Ing. Miroslav Šíša, Ph.D.

Born: 17.3.1975 in Pisek

Education:

1999-2005 Charles University, Faculty of Sciences
Ph.D. thesis entitled: New Brassinosteroids Analogues
Qualification degree: Ph.D.

1995-1999 Institute of Chemical Technology, Prague, Czech Republic
Diploma thesis entitled:
Qualification degree: M.Sc. (Ing.)

1993-1995 Charles University, Faculty of Sciences, Prague, Czech Republic


Professional experiences:

from 2014 Institute of Experimental Botany AS CR, Prague Laboratory of Plant Biotechnologies
Position: research worker

2013-2014 Friedrich-Alexander-Universität Erlangen, Germany
Project: Ferrocene based prodrugs” and “Chemiluminiscent DNA labeling
Advisor: Prof. A. Mokhir

2011-2013 University of Basel, Switzerland
Project: Lewis Acid Catalysed Inverse Electron-Demand Diels-Alder Reaction – A New Synthetic Entry to Steroids
Advisor: Prof. H. A. Wegner

2010-2011 University of Free States, Department of Organic Chemistry, Bloemfontein, South Africa
Project: The development of novel methodology to synthesize unavailable 3 and 4-coupled proanthocyanidins in sufficient quantities for bioassay testing and drug development
Advisor: Prof Jan (H) Van der Westhuizen

2009 Academy of Sciences of the Czech Republic, Palacky University, Olomouc, Czech Republic
Position: Postdoctoral Research Assistant
Project: Fluorescent brassinosteroids labeling for biosynthesis studies
Advisor: Prof. M. Strnad

2008-2009 PCB-UB-IRBB, Department of Chemistry and Molecular Pharmacology, Barcelona, Spain
Position: Postdoctoral Research Assistant
Project: Synthesis of natural Aplicyanins and analogues and evaluation of its anticancer biological activity
Advisors: Prof. Dr. F. Albericio, Prof. Dr. M. Alvareare

2006-2008 Department of Biologic and Organic Chemistry, Barcelona, Spain
Position: Postdoctoral Research Assistant
Project: An approach to the design of chemical chaperones as new potential therapeutic agents
Advisor: Prof. Dr. A. Delgado

2005-2006 Academy of Sciences of the Czech Republic, Institute of Organic Chemistry and Biochemistry, Department of Medicinal Steroids, Prague, Czech Republic
Position: Postdoctoral Research Assistant
Project: SAR of brassinosteroids

2004-2005 IQS, University Ramon Llull, Barcelona, Spain
Ph.D. intership
Project: Brassinolide side chain simulation and molecular modeling explanation of SAR

1999-2005 Academy of Sciences of the Czech Republic, Institute of Organic Chemistry and Biochemistry, Department of Medicinal Steroids, Prague, Czech Republic
Ph.D. in organic chemistry
Project: New Brassinosteroids Analogues
Advisor: RNDr. Ladislav Kohout, DrSc.

1999 Max Planck Institute, Cologne, Germany
Ph.D. intership
Project: Research on Brassinosteroids

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